Functionalized carbon nanotube
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Nanotubes
usually
need to be funcionalized with chemical
groups to change their surface properties, such as hydrophilicity,
charge, and chemical activities, thereby to prelude the
biomolecule
immobilization for biology applications. Typically, the nanotube are
functionalized with carboxyl groups. Then the nanoutbes will be
amenable to covalent linkage to molecules with amine groups. This
strategy has been widely employed for immobilizing oligonucleotides,
peptides, antibodies, enzymes, proteins, and small signal molecules
onto carbon nanotubes. In NanoLab, the carboxyl functionalized
multi-walled carbon nanotube is available for both research and
industrial productions.
Because
of the enhanced hydrophilicity by the functionalization, the
nanotube becomes very water soluble. NanoLabbiosystems is supplying
such high quality funtionalized nanotube solution now. Without any
supplement of any surfactant, the concentration of the nanotube
solution can be as high as 3 g/L. The water solution at 300 mg/L can be
stable on shelf for more than 3 months.
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Biointerface
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Carbon nanotubes can be
assembled
on a surface as a monolayer. The monolayer can be patterned into
an array or special
shape. The functional groups on nanotubes remain robust for
immobilizaitons. The presence of nanotube largely changes the
surface
in its area and susceptibility to the molecular immobilization. Some
potential applications will be found in the microarray, protein
chip,
biosensor, surface modification for implantable devices, molecule
delivery, and receptor mediated cell growth, differentiation and
apoptosis, etc. Especially, the glass substrate with
a monolayer is still
transparant and does not show significant optic cut-off.
So the optic microscopy will remain applicable to the
corresponding studies.
Nanotube
monolayer under SEM
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Nanotube monolayer under AFM
diameter range measured under TEM
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Biosensor
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Carbon nanotubes are electrically
conductive and can be
turned into electrodes. In case of electrochemical detection, nanotube
was
found to be able to accelerate the electron transportation and thereby
increase
the temporal response to reactants. NanoLabbiosystems fabricates the
biosensor
electrodes with either CVD or PECVD nanotubes.
One of the art
of NanoLab is to make carbon
nanotube array at low site density. Because of the PECVD growth mechanism, the nanotubes are vertically aligned. Each nanotube is a single nanoelectrode unit. With our expertise of biomolecule immobilization, enzymes such as glucose oxidase and horseradish peroxidase can be attached to the nanoelectrodes and turn them into biosensors with the sensitivity to specific species in the biological samples.
Another form of biosensor is made of CVD nanotubes. The nanotubes can form a ultra porous structure with extreme large surface to volume ratio. Therefore the reactive surface for detection will be drastically enhanced in contrast to the conventional biosensors.
If you recognize the importance of
the product to your research, please do not hesitate to contact us at info@nanolabbiosystems.com.
It is our pleasure to be consulted for the best application of the nanosensor
in your work. Our goal is to make you outstanding!
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